| 000 | 02981namaa2200409uu 4500 | ||
|---|---|---|---|
| 001 | oapen49424 | ||
| 003 | oapen | ||
| 005 | 20240507100205.0 | ||
| 006 | m o d | ||
| 007 | cr|mn|---annan | ||
| 008 | 210607s2017 xx |||||o ||| 0|eng d | ||
| 020 | _a9781782624356 | ||
| 020 | _a9781782626602 | ||
| 024 | 7 |
_a10.1039/9781782626602 _2doi |
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| 040 |
_aoapen _coapen |
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| 041 | 0 | _aeng | |
| 042 | _adc | ||
| 072 | 7 |
_aMBGR _2bicssc |
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| 072 | 7 |
_aMKN _2bicssc |
|
| 100 | 1 |
_aVaiserman, Alexander _4edt |
|
| 245 | 1 | 0 |
_aAnti-aging Drugs _bFrom Basic Research to Clinical Practice |
| 260 |
_aCambridge _bRoyal Society of Chemistry _c2017 |
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| 300 | _a1 online resource (570 p.) | ||
| 336 |
_atext _btxt _2rdacontent |
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| 337 |
_acomputer _bc _2rdamedia |
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| 338 |
_aonline resource _bcr _2rdacarrier |
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| 506 | 0 |
_aFree-to-read _fUnrestricted online access _2star |
|
| 520 | _aAging is a natural phenomenon that is peculiar to all living things. However, accumulating findings indicate that senescence could be postponed or prevented by certain approaches. Substantial evidence has emerged supporting the possibility of radical human health and lifespan extension, in particular through pharmacological modulation of aging. A number of natural dietary ingredients and synthetic drugs have been assumed to have geroprotective potential. In the development of anti-aging therapeutics, several cell, insect, and animal models may provide useful starting points prior to human studies. This book provides an overview of current research aimed to search for life-extending medications and describes pharmacological aspects of anti-aging medicine. Readers are introduced to the fascinating historical background of geroprotection in the first chapter. In-depth information on models for investigating geroprotective drugs precedes a section covering anti-aging properties of pharmaceutical compounds, such as calorie restriction mimetics, autophagy inducers, senolytics and mitochondrial antioxidants. Finally, strategies to translate discoveries from aging research into drugs and healthcare policy perspectives on anti-ageing medicine are provided to give a complete picture of the field. A timely and carefully edited collection of chapters by leading researchers in the field, this book will be a fascinating and useful resource for pharmacologists, gerontologists and any scientifically interested person wishing to know more about the current status of research into anti-aging remedies, challenges and opportunities. | ||
| 540 |
_aAll rights reserved _uhttp://oapen.org/content/about-rights |
||
| 546 | _aEnglish | ||
| 650 | 7 |
_aGeriatric medicine _2bicssc |
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| 650 | 7 |
_aMedical research _2bicssc |
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| 653 | _aanti-aging medicine; research; clinical practice | ||
| 700 | 1 |
_aVaiserman, Alexander _4oth |
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| 793 | 0 | _aOAPEN Library. | |
| 856 | 4 | 0 |
_uhttps://library.oapen.org/handle/20.500.12657/49424 _70 _zFree-to-read: OAPEN Library: description of the publication |
| 999 |
_c36500 _d36500 |
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