000 02649namaa2200397uu 4500
001 oapen50310
003 oapen
005 20240507100205.0
006 m o d
007 cr|mn|---annan
008 210804s2020 xx |||||o ||| 0|eng d
020 _a9783030291785
040 _aoapen
_coapen
041 0 _aeng
042 _adc
072 7 _aMKG
_2bicssc
100 1 _aLa Caze, Adam
_4edt
245 1 0 _aUncertainty in Pharmacology
_bEpistemology, Methods and Decisions
260 _bSpringer Nature
_c2020
300 _a1 online resource
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
490 1 _aBoston Studies in the Philosophy and History of Science
_v338
506 0 _aFree-to-read
_fUnrestricted online access
_2star
520 _aThis volume covers a wide range of topics concerning methodological, epistemological, and regulatory-ethical issues around pharmacology. The book focuses in particular on the diverse sources of uncertainty, the different kinds of uncertainty that there are, and the diverse ways in which these uncertainties are (or could be) addressed. Compared with the more basic sciences, such as chemistry or biology, pharmacology works across diverse observable levels of reality: although the first step in the causal chain leading to the therapeutic outcome takes place at the biochemical level, the end-effect is a clinically observable result-which is influenced not only by biological actions, but also psychological and social phenomena. Issues of causality and evidence must be treated with these specific aspects in mind. In covering these issues, the book opens up a common domain of investigation which intersects the deeply intertwined dimensions of pharmacological research, pharmaceutical regulation and the related economic environment. The book is a collective endeavour with in-depth contributions from experts in pharmacology, philosophy of medicine, statistics, scientific methodology, formal and social epistemology, working in constant dialogue across disciplinary boundaries.
540 _aAll rights reserved
_uhttp://oapen.org/content/about-rights
546 _aEnglish
650 7 _aPharmacology
_2bicssc
653 _aCausal Inference, Evidence, Social Epistemology of Medicine, Values in the Sciences, Evidence Amlgamation.
700 1 _aLa Caze, Adam
_4oth
700 1 _aOsimani, Barbara
_4edt
700 1 _aOsimani, Barbara
_4oth
793 0 _aOAPEN Library.
856 4 0 _uhttps://library.oapen.org/handle/20.500.12657/50310
_70
_zFree-to-read: OAPEN Library: description of the publication
999 _c36496
_d36496